Article
Psoriasis patients who are homozygous for the HLA-Cw*0602 allele have a 2.5-fold increased risk of developing psoriasis compared with Cw6 heterozygotes.
The British journal of dermatology - 1 Feb 2003
Gudjonsson J E, Karason A, Antonsdottir A, Runarsdottir E H, Hauksson V B, Upmanyu R, Gulcher J, Stefansson K, Valdimarsson H
Abstract excerpt
BACKGROUND: Psoriasis is strongly associated with certain human leucocyte-associated antigens, especially HLA-Cw*0602. Patients who are HLA-Cw*0602 positive have been reported to have more active disease and a younger age at disease onset than HLA-Cw6-negative patients. OBJECTIVES: To ascertain whether there are differences in the clinical features and relative risk between HLA-Cw*0602 homozygous and heterozygous...
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