Article
Analysis of T102C 5HT2A polymorphism in Brazilian psychiatric inpatients: relationship with suicidal behavior.
Cellular and molecular neurobiology - 1 Dec 2002
Correa H, De Marco L, Boson W, Viana M M, Lima V F S, Campi-Azevedo A C, Noronha J C M, Guatimosim C, Romano-Silva Marco A
Abstract excerpt
1. Central serotonergic dysfunction and genetic factors are associated with suicidal behavior in psychiatric patients. The goal of this study was to examine the association between the 5-HT2A gene polymorphism (102T/C) and suicide in a sample of Brazilian psychiatric inpatients. 2. We studied 225 subjects. Genotypic frequencies were obtained after DNA extraction and the region of 5-HT2A/T102C containing the...
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