Article
Association study of two polymorphisms of the serotonin-2A receptor gene and suicide attempts.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2008
Vaquero-Lorenzo Concepcion, Baca-Garcia Enrique, Diaz-Hernandez Montserrat, Perez-Rodriguez M Mercedes, Fernandez-Navarro Pablo, Giner Lucas, Carballo Juan J, Saiz-Ruiz Jeronimo, Fernandez-Piqueras Jose, Baldomero Enrique Baca, de Leon Jose, Oquendo Maria A
Abstract excerpt
Serotonin (5-HT) receptors may have a role in suicidal behavior. Previous studies have shown an association between the T102C polymorphism of the 5-HT2a receptor gene and suicidal behavior. However, negative findings have also been reported. We examined the association between the T102C and C1354T (His452Tyr) polymorphisms of the 5-HT2a receptor gene and suicide attempts. Four hundred forty-one suicide...
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