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Quantitative Gstp1 Methylation Clearly Distinguishes Benign Prostatic Tissue And Limited Prostate Adenocarcinoma

1 Mar 2003

Abstract excerpt

PURPOSE: Hypermethylation of the glutathione S-transferase gene (GSTP1) is the most common (greater than 90%) reported epigenetic alteration in prostate cancer. It occurs early in cancer progression and it is a promising marker for detecting organ confined disease. To evaluate its use as a diagnostic tool for cancer we used quantitative GSTP1 methylation to test for the presence of cancer in 45 prostate needle...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 12576869
DOI: 10.1097/01.ju.0000049627.90307.4d

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