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Article

Effect of time of harvest of budded virus on the selection of baculovirus FP mutants in cell culture.

Biotechnology progress - 1 Jan 2000

Lua Linda H L, Reid Steven

Abstract excerpt

Rapid formation and selection of FP (few polyhedra) mutants occurs during serial passaging of Helicoverpa armigera nucleopolyhedrovirus (HaSNPV) in insect cell culture. The production of HaSNPV for use as biopesticides requires the passaging of the virus over a number of passages to produce enough virus inoculum for large-scale fermentation. During serial passaging in cell culture, FP mutants were rapidly...

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PMID: 12573032
DOI: 10.1021/bp025577u

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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