Article
Gender dimorphism in the role of cycle (BMAL1) in rest, rest regulation, and longevity in Drosophila melanogaster.
Journal of biological rhythms - 1 Feb 2003
Hendricks Joan C, Lu Sumei, Kume Kazuhiko, Yin Jerry C P, Yang Zhaohai, Sehgal Amita
Abstract excerpt
The central clock is generally thought to provide timing information for rest/activity but not to otherwise participate in regulation of these states. To test the hypothesis that genes that are components of the molecular clock also regulate rest, the authors quantified the duration and intensity of consolidated rest and activity for the four viable Drosophila mutations of the central clock that lead to...
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