Article
[Study on the dynamic changes of retinoblastoma gene of SO-Rb50 cell line].
Yan ke xue bao = Eye science - 1 Jun 2001
Feng G, Li H, Yi Y, Zheng J, Zhang Q, Wang X, Du C
Abstract excerpt
PURPOSE: To study the dynamic changes of Retinoblastoma Gene of SO-Rb50 cell line. METHODS: 1) Southern blot hybridization was used to analyse the tumor cell DNA of 327th passage of SO-Rb50 cell line. 2) A promoter and 27 exons of Rb gene were screened exon-by-exon by using PCR-SSCP at 415th and 713th passages of SO-Rb50 cell line. 3) Three cell cloning strains named as MC2, MC3 and MC4 were isolated by single...
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