Article
Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A.
Biochemical and biophysical research communications - 7 Feb 2003
Umehara Hiroshi, Nishii Yoichi, Morishima Masaki, Kakehi Yoshiyuki, Kioka Noriyuki, Amachi Teruo, Koizumi Jun, Hagiwara Masatoshi, Ueda Kazumitsu
Abstract excerpt
The C-half of cisplatin resistance-associated overexpressed protein (CROP), an SR-related protein, comprises domains rich in arginine and glutamate residues (RE domain), and is rich in arginine and serine residues (RS domain). We analyzed the role of the individual domains of CROP in cellular localization, subnuclear localization, and protein-protein interaction. CROP fused with green fluorescent protein,...
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