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Article

Impact of clade diversity on HIV-1 virulence, antiretroviral drug sensitivity and drug resistance.

The Journal of antimicrobial chemotherapy - 1 Feb 2003

Spira Shalom, Wainberg Mark A, Loemba Hugues, Turner Dan, Brenner Bluma G

Abstract excerpt

HIV-1 infection is characterized by genetic diversity wherein distinct viral subtypes (clades A, B, C, D, E, F, G, K and O) are expanding in different geographical regions. This article deals with the topic of HIV-1 subtype diversity in the context of sensitivity to antiretroviral drugs, drug resistance and viral fitness. Increasing evidence suggests that all clades of HIV probably display similar sensitivity to...

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Identifiers

PMID: 12562686
DOI: 10.1093/jac/dkg079

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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