Article
MICA4/HLA-DRB1*04/TNF1 haplotype is associated with mixed connective tissue disease in Swedish patients.
Human immunology - 1 Feb 2003
Hassan Adla B, Nikitina-Zake Liene, Padyukov Leonid, Karlsson Göran, Gupta Manu, Lundberg Ingrid E, Sanjeevi Carani B
Abstract excerpt
In order to investigate major histocompatibility complex (MHC) class I chain-related gene A (MICA), tumor necrosis factor (TNFa), -308TNFA, and human leukocyte antigen (HLA-DR/DQ) polymorphisms in mixed connective tissue disease (MCTD), we analyzed 24 patients and 229 healthy controls from Sweden. MICA and TNFa typing was performed by polymerase chain reaction (PCR) and genotyping. HLA-DR and -DQ were genotyped...
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