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Article

Monocyte CD40 expression in severe sepsis.

Shock (Augusta, Ga.) - 1 Jan 2003

Sugimoto Kenji, Galle Cécile, Preiser Jean-Charles, Creteur Jacques, Vincent Jean-Louis, Pradier Olivier

Abstract excerpt

D40 is a cell surface protein belonging to the tumor necrosis factor (TNF) receptor family. Ligation of monocyte CD40 by the T cell-derived CD40 ligand can trigger the production of various mediators, the transcription and activation of enzymes, and the upregulation of costimulatory molecules involved in the pathogenesis of sepsis. To test the hypothesis that CD40 is expressed on the surface of monocytes during...

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Identifiers

PMID: 12558139
DOI: 10.1097/00024382-200301000-00005

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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