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Glutathione S-transferase M1 and T1 genetic polymorphisms, alcohol consumption and breast cancer risk

1 Jan 2003

Abstract excerpt

Alcohol consumption has been inconsistently associated with breast cancer risk. Recent studies suggest that genetic polymorphisms of glutathione S-transferases (GSTs) may modify this relation. To determine if breast cancer risk is associated with GSTM1 and GSTT1 genetic polymorphisms, and to evaluate the effect modification between GST genotypes and alcohol consumption in the risk of breast cancer, we conducted a...

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PMID: 12556960
DOI: 10.1038/sj.bjc.6600708

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