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Article

Genomic organization and evolution of the CX3CR1/CCR8 chemokine receptor locus.

The Journal of biological chemistry - 4 Apr 2003

DeVries Mark E, Cao Henian, Wang Jian, Xu Luoling, Kelvin Alyson A, Ran Longsi, Chau Luan A, Madrenas Joaquin, Hegele Robert A, Kelvin David J

Abstract excerpt

The chemokine receptors CCR8 and CX3CR1 are key players in adaptive immunity and are co-receptors for human immunodeficiency virus. We describe here the genomic organization and evolutionary history of both of these genes. CX3CR1 has three promoters that transcribe three separate exons that are spliced with a fourth exon containing the coding region. CCR8 has two promoters. One promoter produces a transcript of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12551893
DOI: 10.1074/jbc.M211422200

Genes

CCR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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