Article
Three electrophysiological phenotypes of cultured human umbilical vein endothelial cells.
General physiology and biophysics - 1 Sept 2002
Yu K, Ruan D Y, Ge S Y
Abstract excerpt
The conventional whole cell patch-clamp technique was used to measure the resting membrane conductance and membrane currents of nonstimulated cultured human umbilical vein endothelial cells (HUVECs) in different ionic conditions. Three electrophysiological phenotypes of cultured HUVECs (n = 122) were determined: first, 20% of cells as type I mainly displaying the inwardly rectifying potassium current (IKi);...
Topics
- Cells, Cultured
- Chlorides
- Electric Conductivity
- Electrophysiology
- Endothelium, Vascular
- Humans
- Ion Channel Gating
- Membrane Potentials
- Patch-Clamp Techniques
- Phenotype
- Potassium
- Potassium Channels
- Potassium Channels, Inwardly Rectifying
- Potassium Channels, Tandem Pore Domain
- Umbilical Veins