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Article

Metabolic flux redistribution in Corynebacterium glutamicum in response to osmotic stress.

Applied microbiology and biotechnology - 1 Jan 2003

Varela C, Agosin E, Baez M, Klapa M, Stephanopoulos G

Abstract excerpt

Osmotic stress constitutes a major bacterial stress factor in the soil and during industrial fermentation. In this paper, we quantified the metabolic response, in terms of metabolic flux redistribution, of a lysine-overproducing strain of Corynebacterium glutamicum grown under continuous culture, to gradually increasing osmolality. Oxygen and carbon dioxide evolution rates, and the changes in concentration of...

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PMID: 12536254
DOI: 10.1007/s00253-002-1120-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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