Article
A defect of Kap104 alleviates the requirement of mitotic exit network gene functions in Saccharomyces cerevisiae.
Genetics - 1 Dec 2002
Asakawa Kazuhide, Toh-e Akio
Abstract excerpt
A subgroup of the karyopherin beta (also called importin beta) protein that includes budding yeast Kap104 and human transportin/karyopherin beta2 is reported to function as a receptor for the transport of mRNA-binding proteins into the nucleus. We identified KAP104 as a responsible gene for a suppressor mutation of cdc15-2. We found that the kap104-E604K mutation suppressed the temperature-sensitive growth of...
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