Article
[Lung cancer risk associated with genetic polymorphism in myeloperoxidase (-463 G/A) in a Chinese population].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 May 2002
Lu Wenfu, Qi Jun, Xing Deyin, Tan Wen, Miao Xiaoping, Su Wei, Wu Min, Lin Dongxin
Abstract excerpt
OBJECTIVE: To examine the relationship between susceptibility to lung cancer among Chinese and genetic polymorphism at nucleotide -463 (G/A) in myeloperoxidase (MPO), an enzyme found in lysosomes of phagocytes and involved in the formation of hydroxyl radicals and activation of various smoking-related carcinogens. METHODS: The association of this polymorphism with lung cancer in a hospital-based case-control...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
