Article
Influence of ScaI and natriuretic peptide (NP) clearance receptor polymorphisms of the NP System on NP concentration in chronic heart failure.
Clinical chemistry - 1 Nov 2007
Vassalle Cristina, Andreassi Maria Grazia, Prontera Concetta, Fontana Marianna, Zyw Luc, Passino Claudio, Emdin Michele
Abstract excerpt
BACKGROUND: Genetic variants related to the natriuretic peptide (NP) system [ScaI mutated allele (A1) of the atrial NP (ANP) gene and the C variant of the natriuretic peptide clearance receptor (NPRC) gene] have been identified as independent risk factors for cardiovascular morbidity and mortality. Despite the importance of NPs in heart failure (HF), the role of these polymorphisms in HF has not been evaluated....
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