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The Sperm Chromatin Dispersion Test: A Simple Method for the Determination of Sperm DNA Fragmentation

2 Jan 2003

Abstract excerpt

Sperm DNA fragmentation is being increasingly recognized as an important cause of infertility. We herein describe the Sperm Chromatin Dispersion (SCD) test, a novel assay for sperm DNA fragmentation in semen. The SCD test is based on the principle that sperm with fragmented DNA fail to produce the characteristic halo of dispersed DNA loops that is observed in sperm with non-fragmented DNA, following acid...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 12514084
DOI: 10.1002/j.1939-4640.2003.tb02641.x

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