Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sperm Chromatin Dispersion Test Detects Sperm DNA Fragmentation Mainly Associated with Unviable Spermatozoa and Underestimates the Values with Respect to TUNEL Assay

19 Apr 2024

Abstract excerpt

Several clinical laboratories assess sperm DNA fragmentation (sDF) in addition to semen analysis in male infertility diagnosis. Among tests evaluating sDF, TUNEL (Terminal deoxynucleotidyl transferase dUTP nick end labeling) and SCD (Sperm Chromatin Dispersion) are widely used. Our lab developed a modified version of TUNEL (TUNEL/PI) able to distinguish two sperm populations (PI Brighter and PI Dimmer)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive Biology and Fertility
Share to Reproductive Health and Technologies
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38674066
DOI: 10.3390/ijms25084481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sperm Chromatin Dispersion Test Detects Sperm DNA Fragmentation Mainly Associated with Unviable Spermatozoa and Underestimates the Values with Respect to TUNEL AssayPMID 38674066Read ↗

TUNEL labeling with BrdUTP/anti-BrdUTP greatly underestimates the level of sperm DNA fragmentation in semen evaluationSemantic proximity Read ↗

Nuclear staining identifies two populations of human sperm with different DNA fragmentation extent and relationship with semen parametersSemantic proximity Read ↗

Comparison of Chromatin Assays for DNA Fragmentation Evaluation in Human SpermSemantic proximity Read ↗

TUNEL assay: Establishing a sperm DNA fragmentation cut‐off value for Egyptian infertile menSemantic proximity Read ↗

Inter‐and Intra‐Laboratory Standardization of TUNEL Assay for Assessment of Sperm DNA FragmentationSemantic proximity Read ↗

What should be done for men with sperm DNA fragmentation?Semantic proximity Read ↗

Evaluation of sperm DNA fragmentation in male infertilitySemantic proximity Read ↗

TUNEL assay—Standardized method for testing sperm DNA fragmentationSemantic proximity Read ↗

Progress in Research on Sperm DNA FragmentationSemantic proximity Read ↗

Sperm chromatin structure assay (SCSA®) and flow cytometry-assisted TUNEL assay provide a concordant assessment of sperm DNA fragmentation as a function of age in a large cohort of approximately 10,000 patientsSemantic proximity Read ↗

Comprehensive analysis of sperm DNA fragmentation by five different assays: TUNEL assay, SCSA, SCD test and alkaline and neutral Comet assaySemantic proximity Read ↗

Correlation between the DNA fragmentation index (DFI) and sperm morphology of infertile patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.