Article
[Biopharmaceutical studies on molecular mechanisms of membrane transport].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Dec 2002
Tsuji Akira
Abstract excerpt
By incorporating the transporter-mediated or receptor-mediated transport process in physiologically based pharmacokinetic models, we succeeded in the quantitative prediction of plasma and tissue concentrations of beta-lactam antibiotics, insulin, pentazocine, quinolone antibacterial agents, and inaperizone and digoxin. The author's research on transporter-mediated pharmacokinetics focuses on the molecular and...
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