Article
Carnitine transport by organic cation transporters and systemic carnitine deficiency.
Molecular genetics and metabolism - 1 Aug 2001
Lahjouji K, Mitchell G A, Qureshi I A
Abstract excerpt
The intracellular homeostasis is controlled by different membrane transporters. Organic cation transporters function primarily in the elimination of cationic drugs, endogenous amines, and other xenobiotics in tissues such as the kidney, intestine, and liver. Among these molecules, carnitine is an endogenous amine which is an essential cofactor for mitochondrial beta-oxidation. Recently, a new family of...
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