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Article

Role of ALDP (ABCD1) and mitochondria in X-linked adrenoleukodystrophy.

Molecular and cellular biology - 1 Jan 2003

McGuinness M C, Lu J-F, Zhang H-P, Dong G-X, Heinzer A K, Watkins P A, Powers J, Smith K D

Abstract excerpt

Peroxisomal disorders have been associated with malfunction of peroxisomal metabolic pathways, but the pathogenesis of these disorders is largely unknown. X-linked adrenoleukodystrophy (X-ALD) is associated with elevated levels of very-long-chain fatty acids (VLCFA; C(>22:0)) that have been attributed to reduced peroxisomal VLCFA beta-oxidation activity. Previously, our laboratory and others have reported...

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Share to Adrenal Glands
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Share to ATP Binding Cassette Transporter, Subfamily D, Member 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12509471
DOI: 10.1128/MCB.23.2.744-753.2003
PMCID: PMC151532

Genes

ABCD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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