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Article

Adrenoleukodystrophy gene: unexpected homology to a protein involved in peroxisome biogenesis.

Biochimie - 1 Jan 1993

Aubourg P, Mosser J, Douar A M, Sarde C O, Lopez J, Mandel J L

Abstract excerpt

Adrenoleukodystrophy (ALD) is an X-linked peroxisomal disorder characterized by a progressive demyelination of the central nervous system and adrenal insufficiency. Clinical phenotypes of different severity are frequently observed within the same kindred. ALD is characterized biochemically by the accumulation of very-long-chain fatty acids (VLCFA) due to an impairment in the beta-oxidation of these fatty acids in...

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Identifiers

PMID: 8507690
DOI: 10.1016/0300-9084(93)90089-b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Adrenoleukodystrophy gene: unexpected homology to a protein involved in peroxisome biogenesis.PMID 8507690Read ↗

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A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.Semantic proximity Read ↗

Mutational analysis of patients with X-linked adrenoleukodystrophy.Semantic proximity Read ↗

X-linked adrenoleukodystrophy: clinical, metabolic, genetic and pathophysiological aspects.Semantic proximity Read ↗

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