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Article

Adrenoleukodystrophy gene: unexpected homology to a protein involved in peroxisome biogenesis.

Biochimie - 1 Jan 1993

Aubourg P, Mosser J, Douar A M, Sarde C O, Lopez J, Mandel J L

Abstract excerpt

Adrenoleukodystrophy (ALD) is an X-linked peroxisomal disorder characterized by a progressive demyelination of the central nervous system and adrenal insufficiency. Clinical phenotypes of different severity are frequently observed within the same kindred. ALD is characterized biochemically by the...

Topics

Adrenoleukodystrophy
Amino Acid Sequence
Cloning, Molecular
Humans
Microbodies
Molecular Sequence Data
Phenotype
Proteins
Sequence Alignment
Sequence Homology, Amino Acid

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8507690
DOI: 10.1016/0300-9084(93)90089-b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8507690-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Adrenoleukodystrophy gene: unexpected homology to a protein involved in peroxisome biogenesis.PMID 8507690Read ↗

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Identification of mutations in the ALD-gene of 20 families with adrenoleukodystrophy/adrenomyeloneuropathy.Semantic proximity Read ↗

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