Article
Molecular and pharmacological characterisation of the MSH-R alleles in Swiss cattle breeds.
Journal of receptor and signal transduction research - 1 Jan 2000
Graphodatskaya D, Joerg H, Stranzinger G
Abstract excerpt
The coat colour in mammals is determined by the relative amounts of eumelanin (black/brown) and phaeomelanin (red/yellow), produced in melanocytes, which are controlled by melanocyte stimulating hormone receptor (MSH-R). Melanocyte stimulating hormone receptor is activated by alpha-melanocyte-stimulating hormone (alpha-MSH). Stimulated MSH-R activates adenylyl cyclase (AC), thereby increasing the amount of cyclic...
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