Article
Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene.
PloS one - 1 Jan 2015
Dorshorst Ben, Henegar Corneliu, Liao Xiaoping, Sällman Almén Markus, Rubin Carl-Johan, Ito Shosuke, Wakamatsu Kazumasa, Stothard Paul, Van Doormaal Brian, Plastow Graham, Barsh Gregory S, Andersson Leif
Abstract excerpt
Coat color in Holstein dairy cattle is primarily controlled by the melanocortin 1 receptor (MC1R) gene, a central determinant of black (eumelanin) vs. red/brown pheomelanin synthesis across animal species. The major MC1R alleles in Holsteins are Dominant Black (MC1RD) and Recessive Red (MC1Re). A novel form of dominant red coat color was first observed in an animal born in 1980. The mutation underlying this...
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