Article
The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 1995
Klungland H, Våge D I, Gomez-Raya L, Adalsteinsson S, Lien S
Abstract excerpt
The melanocyte-stimulating hormone (MSH) receptor has a major function in the regulation of black (eumelanin) versus red (phaeomelanin) pigment synthesis within melanocytes. We report three alleles of the MSH-receptor gene found in cattle. A point mutation in the dominant allele ED gives black coat color, whereas a frameshift mutation, producing a prematurely terminated receptor, in homozygous e/e animals,...
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