Article
Lack of association between eNOS gene polymorphisms and ischemic heart disease in the Spanish population.
American journal of medical genetics. Part A - 30 Jan 2003
Via Marc, López-Alomar Antonio, Valveny Neus, González-Pérez Emilio, Bao Meritxell, Esteban Esther, Pintó Xavier, Domingo Enric, Moral Pedro
Abstract excerpt
Through the nitric oxide (NO) production in the vascular system, the endothelial nitric oxide synthase (eNOS or NOS3) is a key enzyme in blood pressure regulation and atherosclerosis control. Several previous studies have suggested an important role of eNOS as a genetic risk factor for cardiovascular diseases. In this context, a genetic association study was carried out between two eNOS polymorphisms (the...
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