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[Huntington chorea: genetics and biochemistry, diagnosis and therapy].

Acta pharmaceutica Hungarica - 1 Jan 2002

Borbás Tímea, Hegyesi Hargita

Abstract excerpt

Huntington chorea (HC) is a serious neurodegenerative disease. Its genetic background has recently been discovered by positional cloning due to the enormous progress in molecular biology. This disease is caused by the mutation of CAG, a changeable, repetitive Citosin-Adenin-Guanin trinucleotide sequence. The protein coded by this sequence is called huntingtin. The role of huntingtin is known neither in mutant nor...

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PMID: 12498040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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