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Article

[Analysis of trinucleotide repeat expansion as a new mechanism of mutation in Huntington's chorea: theoretical and applied aspects].

Genetika - 1 Jan 1996

Illarioshkin S N, Ivanova-Smolenskaia I A, Markova E D, Nikol'skaia N N, Chabrashvili T Z, Insarova N G

Abstract excerpt

The Huntington's chorea mutation consists of expansion of trinucleotide CAG repeats in the recently discovered gene IT-15. In this work, for the first time in a population of Russian patients, correlations between the number of copies of CAG repeats and various clinical characteristics of the disease are investigated. It is established that the degree of triplet expansion determines the age of onset of the...

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PMID: 8647411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Molecular genetic testing in the diagnosis of sporadic cases of Huntington's chorea].Semantic proximity Read ↗

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[A new mechanism of mutation in man: expansion of trinucleotide repeats].Semantic proximity Read ↗

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