Article
The mutational spectrum of human autosomal tetranucleotide microsatellites.
Human mutation - 1 Jan 2003
Leopoldino Andréia M, Pena Sérgio D J
Abstract excerpt
We studied by multiplex amplification and single-run electrophoretic analysis 10 microsatellite loci, composed of nine tetranucleotide-repeats (D1S1612, D3S2387, D4S2431, D5S2501, D10S1237, D15S657, D16S2622, D18S1270, and IFNAR-ALU) and one trinucleotide repeat (D2S1353). After elimination of proven null allele events involving D1S1612 and D5S2501 and of all data of D3S2387, in which we suspected but could not...
Topics
- Adult
- Base Sequence
- Child
- DNA Mutational Analysis
- Female
- Gene Frequency
- Humans
- Male
- Meiosis
- Microsatellite Repeats
- Mutation
- Pedigree