Article
[Germline mutations of tetranucleotide DNA repeats in families with normal children and reproductive pathology].
Genetika - 1 Jul 2005
Nikitina T V, Lebedev I N, Sukhanova N N, Nazarenko S A
Abstract excerpt
We have previously reported a high rate of tetranucleotide DNA repeat mutations, including mutations of both germline and somatic origin, in spontaneous human abortuses. To analyze in more detail mutational microsatellite (MS) variability in meiosis and its possible association with disturbed embryonic development, we have conducted a comparative study of mutation rates of a complex of 15 autosomal...
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