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Article

Analysis of two common alpha 1-antitrypsin deficiency alleles (PIZ and PIS) in subjects with periodontitis.

Journal of clinical periodontology - 1 Dec 2002

Scott D A, von Ahsen N, Palmer R M, Wilson R F

Abstract excerpt

BACKGROUND: pi alpha 1-Antitrypsin deficiency is a genetically determined condition resulting in predisposition to certain inflammatory diseases due to a protease: antiprotease imbalance that is exacerbated by tobacco smoking. Limited evidence suggests that there may be a significant enrichment of mild alpha 1-antitrypsin deficiency phenotypes in subjects with chronic inflammatory periodontal disease. OBJECTIVE:...

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Identifiers

PMID: 12492914
DOI: 10.1034/j.1600-051x.2002.291212.x

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