Article
Association between the N-acetylation genetic polymorphism and bronchial asthma.
British journal of clinical pharmacology - 1 Dec 2002
Nacak Muradiye, Aynacioglu A Sükrü, Filiz Ayten, Cascorbi Ingolf, Erdal M Emin, Yilmaz Necat, Ekinci Erhan, Roots Ivar
Abstract excerpt
AIMS: Since polymorphic N-acetyltransferase 2 (NAT2) has been suggested as a susceptibility factor for atopic diseases, the study was undertaken to investigate whether an association exists between acetylation polymorphism and asthma patients with atopy. METHODS: The frequencies of NAT2 alleles and genotypes were determined by PCR/RFLP in a total of 210 asthma patients (extrinsic (n = 108) and intrinsic (n = 102)...
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