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Article

Clinical update of Ad-p53 gene therapy for lung cancer.

Surgical oncology clinics of North America - 1 Jul 2002

Swisher Stephen G, Roth Jack A

Abstract excerpt

These preliminary Phase I and II gene therapy trials in NSCLC have demonstrated that Ad-p53 gene transfer is associated with low toxicity and evidence of antitumoral activity at the locoregional site. Effort to enhance antitumoral efficacy with chemotherapy and radiation therapy have not increased Ad-p53 toxicity and appear to be feasible. Randomized Phase III studies are now needed to determine the potential of...

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Source

Identifiers

PMID: 12487055
DOI: 10.1016/s1055-3207(02)00028-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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