Article
Gene Therapy for Lung Cancer.
Critical reviews in oncogenesis - 1 Jan 2016
Lara-Guerra Humberto, Roth Jack A
Abstract excerpt
Gene therapy was originally conceived to treat monogenic diseases. The replacement of a defective gene with a functional gene can theoretically cure the disease. In cancer, multiple genetic defects are present and the molecular profile changes during the course of the disease, making the replacement of all defective genes impossible. To overcome these difficulties, various gene therapy strategies have been...
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