Article
[Diseases associated with lamin A/C gene defects: what the clinical cardiologist ought to know].
Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology - 1 Feb 2004
Pasotti Michele, Repetto Alessandra, Pisani Angela, Arbustini Eloisa
Abstract excerpt
The nuclear lamina is a proteinaceous layer apposed to the inner nuclear membrane. It is composed of a family of polypeptides, the lamins, highly conserved in evolution. In mammals, 3 lamins, A, B and C have been described with molecular weights ranging from 60,000 to 78,000 Da. Lamins A and C ha...
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