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Article

Cadaverine inhibition of porin plays a role in cell survival at acidic pH.

Journal of bacteriology - 1 Jan 2003

Samartzidou Hrissi, Mehrazin Mahsa, Xu Zhaohui, Benedik Michael J, Delcour Anne H

Abstract excerpt

When grown at acidic pH, Escherichia coli cells secrete cadaverine, a polyamine known to inhibit porin-mediated outer membrane permeability. In order to understand the physiological significance of cadaverine excretion and the inhibition of porins, we isolated an OmpC mutant that showed resistance to spermine during growth and polyamine-resistant porin-mediated fluxes. Here, we show that the addition of exogenous...

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Share to Cell Membrane Permeability
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12486035
DOI: 10.1128/JB.185.1.13-19.2003
PMCID: PMC141942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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