Article
PhoE porin of Escherichia coli and phosphate reversal of acid damage and killing and of acid induction of the CadA gene product.
The Journal of applied bacteriology - 1 Jun 1993
Rowbury R J, Goodson M
Abstract excerpt
The lethal effects of inorganic acid on phoE+ Escherichia coli strains, grown at neutral pHo, were enhanced by chloramphenicol, apparently because some organisms acquire acid tolerance (habituate) during challenge and chloramphenicol stops this. Phosphate (and/or polyphosphate) present during challenge prevented killing and damage by acid to outer membranes, DNA and cellular enzymes but did not prevent acid pHo...
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