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Article

Interferon for treatment of breakthrough infection with hepatitis B virus mutants developing during long-term lamivudine therapy.

Journal of gastroenterology - 1 Jan 2002

Suzuki Fumitaka, Tsubota Akihito, Akuta Norio, Someya Takashi, Kobayashi Masahiro, Suzuki Yoshiyuki, Saitoh Satoshi, Arase Yasuji, Ikeda Kenji, Miyakawa Yuzo, Kumada Hiromitsu

Abstract excerpt

BACKGROUND: We aimed to treat patients with chronic hepatitis B on long-term treatment with lamivudine who developed lamivudine-resistant hepatitis B virus (HBV) mutants along with clinical relapses. METHODS: Of 217 patients with chronic hepatitis B who had been treated with lamivudine for 1-6 years, 23 (11%) developed lamivudine-resistant hepatitis B virus (HBV) mutants. Seven of them, including 1 whose case was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12483247
DOI: 10.1007/s005350200155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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