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Article

The murine COMP (cartilage oligomeric matrix protein) promoter contains a potent transcriptional repressor region.

Osteoarthritis and cartilage - 1 Aug 2002

Han F, Kipnes J R, Li Y, Tuan R S, Hall D J

Abstract excerpt

OBJECTIVE: A subgroup of patients with pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) have been found to harbor mutations within the cartilage oligomeric matrix protein (COMP) gene. These two diseases are autosomal dominant disorders that are characterized by an early onset of osteoarthritis (OA). The COMP gene is expressed primarily in chondrocytes in articular cartilage as well as in...

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Source

Identifiers

PMID: 12479386
DOI: 10.1053/joca.2002.0532

Genes

COMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The murine COMP (cartilage oligomeric matrix protein) promoter contains a potent transcriptional repressor region.PMID 12479386Read ↗

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