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Article

Cartilage oligomeric matrix protein: COMPopathies and beyond.

Matrix biology : journal of the International Society for Matrix Biology - 1 Oct 2018

Posey Karen L, Coustry Francoise, Hecht Jacqueline T

Abstract excerpt

Cartilage oligomeric matrix protein (COMP) is a large pentameric glycoprotein that interacts with multiple extracellular matrix proteins in cartilage and other tissues. While, COMP is known to play a role in collagen secretion and fibrillogenesis, chondrocyte proliferation and mechanical strength of tendons, the complete range of COMP functions remains to be defined. COMPopathies describe pseudoachondroplasia...

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Identifiers

PMID: 29530484
DOI: 10.1016/j.matbio.2018.02.023
PMCID: PMC6129439

Genes

COMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Cartilage oligomeric matrix protein: COMPopathies and beyond.PMID 29530484Read ↗

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Role of TSP-5/COMP in pseudoachondroplasia.Semantic proximity Read ↗

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Novel mutation in exon 18 of the cartilage oligomeric matrix protein gene causes a severe pseudoachondroplasia.Semantic proximity Read ↗

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