Article
Significant linkage on chromosome 10p in families with bulimia nervosa.
American journal of human genetics - 1 Jan 2003
Bulik Cynthia M, Devlin B, Bacanu Silviu-Alin, Thornton Laura, Klump Kelly L, Fichter Manfred M, Halmi Katherine A, Kaplan Allan S, Strober Michael, Woodside D Blake, Bergen Andrew W, Ganjei J Kelly, Crow Scott, Mitchell James, Rotondo Alessandro, Mauri Mauro, Cassano Giovanni, Keel Pamela, Berrettini Wade H, Kaye Walter H
Abstract excerpt
Bulimia nervosa (BN) is strongly familial, and additive genetic effects appear to contribute substantially to the observed familiality. In turn, behavioral components of BN, such as self-induced vomiting, are reliably measured and heritable. To identify regions of the genome harboring genetic variants conferring susceptibility to BN, we conducted a linkage analysis of multiplex families with eating disorders that...
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