Article
Lipid-dependent subcellular relocalization of the acyl chain desaturase in yeast.
Molecular biology of the cell - 1 Dec 2002
Tatzer Verena, Zellnig Günther, Kohlwein Sepp D, Schneiter Roger
Abstract excerpt
The degree of acyl chain desaturation of membrane lipids is a critical determinant of membrane fluidity. Temperature-sensitive mutants of the single essential acyl chain desaturase, Ole1p, of yeast have previously been isolated in screens for mitochondrial inheritance mutants (Stewart, L.C. and Yaffe, M.P. (1991). J. Cell Biol. 115, 1249-1257). We now report that the mutant desaturase relocalizes from its uniform...
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