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Article

Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A

1 Dec 2002

Abstract excerpt

Protein phosphatase (PP2A) 2A is a hetero-trimeric holoenzyme that consists of a core dimer composed of a catalytic subunit that is tightly complexed with the scaffolding subunit PR65/A. This core dimer associates with variable regulatory subunits of the PR55/B, PR61/B', PR72/B" and PR93/PR110/B"' families. As PP2A holoenzymes containing PR55/B have been shown to be involved in the pathogenesis of Alzheimer's...

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PMID: 12473071
DOI: 10.1046/j.1460-9568.2002.02274.x

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