Article
The factor V Leiden (R506Q) mutation and risk of thrombosis in renal transplant recipients.
Transplantation - 27 Aug 1997
Irish A B, Green F R, Gray D W, Morris P J
Abstract excerpt
BACKGROUND: Renal transplantation and chronic renal failure are associated with an increased risk of venous thrombosis and myocardial infarction (MI). We investigated whether resistance to activated protein C due to a mutation in the factor V gene (FV Leiden/FV506Q) may predispose patients to thrombosis. METHODS: Three hundred patients who had undergone renal transplantation were genotyped for the FV mutation....
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