Article
Genetic basis of thoracic aortic aneurysms and dissections.
Current opinion in cardiology - 1 Nov 2002
Hasham Sumera N, Guo Dong-chuan, Milewicz Dianna M
Abstract excerpt
The major diseases affecting the aorta are aortic aneurysms and dissections, which are classified based on anatomic location. Diseases affecting the ascending aorta, such as thoracic aortic aneurysms and type I and II dissections, are primarily associated with medial necrosis on pathologic examination. Medial necrosis is characterized by fragmentation and loss of elastic fibers, loss of smooth muscle cells, and...
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