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Article

Genetic basis of thoracic aortic aneurysms and aortic dissections.

American journal of medical genetics. Part C, Seminars in medical genetics - 15 Nov 2005

Pannu Hariyadarshi, Tran-Fadulu Van, Milewicz Dianna M

Abstract excerpt

Ascending thoracic aortic aneurysms leading to type A dissections (TAAD) can occur in association with a genetic syndrome, such as Marfan syndrome (MFS), or as an autosomal dominant disorder in the absence of syndromic features, termed familial TAAD. Familial TAAD demonstrates genetic heterogeneity, and linkage studies have identified three TAAD loci at 5q13-14 (TAAD1), 11q23 (FAA1), and 3p24-25 (TAAD2). The...

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Identifiers

PMID: 16273536
DOI: 10.1002/ajmg.c.30069

Genes

TGFBR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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