Article
The eyes of mito-mouse: mouse models of mitochondrial disease.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society - 1 Dec 2002
Biousse Valérie, Pardue Machelle T, Wallace Douglas C, Newman Nancy J
Abstract excerpt
The recent creation of several mouse models of mitochondrial diseases has provided new insights into the understanding of human mitochondrial disorders. Whether these animals have clinical or histologic ophthalmologic abnormalities is of great interest given the high frequency of such abnormalities in humans with mitochondrial disorders. In this article, we describe the currently available mouse models for...
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