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Article

Mouse models of human ocular disease for translational research.

PloS one - 1 Jan 2017

Krebs Mark P, Collin Gayle B, Hicks Wanda L, Yu Minzhong, Charette Jeremy R, Shi Lan Ying, Wang Jieping, Naggert Jürgen K, Peachey Neal S, Nishina Patsy M

Abstract excerpt

Mouse models provide a valuable tool for exploring pathogenic mechanisms underlying inherited human disease. Here, we describe seven mouse models identified through the Translational Vision Research Models (TVRM) program, each carrying a new allele of a gene previously linked to retinal developmental and/or degenerative disease. The mutations include four alleles of three genes linked to human nonsyndromic ocular...

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Identifiers

PMID: 28859131
DOI: 10.1371/journal.pone.0183837
PMCID: PMC5578669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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